Emerging Roles of Lipid Metabolism in Cancer Metastasis

Host

Ana Luísa Correia, PhD, Cancer Dormancy & Immunity

Venue

Seminar room

Abstract

Our lab is focused on understanding how metastasizing cells change after leaving the primary tumor to successfully adapt to the different environments in the new tissues. In this regard, several nutrients and metabolites available at distant organs have been implicated in supporting the nesting of disseminated cancer cells. Moreover, we study how both cell-intrinsic and environment-influenced factors intensify heterogenic metabolic reprogramming in tumor cells to fuel invasion, survival and seeding in the distant organ.

Biography

Patricia altea-Manzano holds a PhD in Biomedicine from the University of Granada (Spain) and is an expert in cancer cell biology, with a focus on tumor metabolism, metastasis, and targeted therapies. She has conducted research in renowned institutions across Spain, the UK, the US, and Belgium, including postdoctoral work in Prof. Sarah-Maria Fendt’s lab at VIB-KU Leuven. Currently, she leads the Metabolic and Signaling in Cancer Lab at CABIMER (Seville), holding the prestigious Ramón y Cajal Program from Spain. Her research aims to uncover how cellular metabolism drives cancer progression to develop innovative treatments for metastatic disease. Patricia has received prestigious funding, including an ERC Starting Grant, and her work appears in important journals such as Nature, Nature Cancer, and Molecular Cell.

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About CR Colloquia Series

Champalimaud Research (CR) Colloquia Series is a seminar programme organised by the Champalimaud Centre for the Unknown to promote the discussion about the most interesting and significant questions in neuroscience and physiology & cancer with appointed speakers by the CR Community.