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Research Groups
Cancer and Stem Cell Biology

About

Sánchez Danés Lab

Sánchez Danés Lab

Most tumours are heterogeneous at the cellular and (epi)genetic levels. This heterogeneity has been proposed to be responsible for tumour progression, metastasis and resistance to therapy. Our goal is to understand the contribution of the different tumour cell populations and genetic alterations to cancer progression and response to therapy. We do that by combining genetic lineage tracing, clonal analysis, imaging techniques, tumour organoid cultures and functional experiments in vivo and in vitro. We use the most frequent human cancer – basal cell carcinoma – and one of the most common pediatric cancers – medulloblastoma – as the models for our studies. Both types of cancer arise upon the constitutive activation of the Hedgehog signalling pathway.

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Opportunities

If you are interested in joining our group, please contact Adriana Sánchez Danés via email.

Projects

Sánchez Danés Lab

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Team

Sánchez Danés Lab

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Adriana Sánchez Danés

Principal Investigator

Ana Sofia Marques

PhD Student

Laura Ward

Project Manager

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