One of the hallmarks of multiple myeloma (MM), a cancer of the bone marrow and one of the most frequent haematological cancers worldwide, is the disruption of the patients’ immune system, which allows the cancer to progress. Now, a study performed by Cristina João, who leads the Myeloma and Lymphoma Research Group at the Champalimaud Centre for the Unknown, and her colleagues, shows how so-called extracellular vesicles (EV’s) released by multiple myeloma cells can drive the disruption of the immune system.

Adjuvant cancer treatments are the most conventional, most classic therapeutic approach to cancer. Here, the first step is usually surgery to remove the tumour, followed by chemotherapy, radiotherapy or other additional treatments to consolidate the surgery’s results.

It is with great enthusiasm that we invite you to register for the second hybrid edition of CRSy, to be held at the Champalimaud Centre for the Unknown (CCU), in a stunning setting on the waterfront in Lisbon, Portugal, from October 19–21.

The overall goal of this event is to highlight examples from international funding entities that are either already piloting or considering implementing different models to allocate research funds, with a particular emphasis on the partial randomisation process, and highlight the perspective of researchers on this topic.

The session will end with a roundtable discussion featuring the views from researchers hosted by Portuguese institutions on whether partial randomisation is an appropriate alternative to the current peer review process.  

Early diagnosis aims to detect cancer in its early stages when it is potentially curable. This can apply not only to people who already have symptoms of a given cancer, but also to those who, not having any symptom, are subject to known risk factors that justify this approach.

Mr. P. started to be followed at the smoking cessation consultation of the Champalimaud Foundation in mid-2018. He had been a smoker for 33 years, and in 2018, he smoked around one pack of cigarettes a day. His first attempt to quit failed, but Mr. P. never quit the consultation and never gave up on quitting smoking. He finally achieved his goal in mid-2020 through a multidisciplinary approach (including psychology and psychiatry consultations) – and, to this day, has never smoked again.

To know more about this research:

Digest

Scientific Article

Funded by the MCSA & Citizens action - RAISE is built around a concept of co-creation that will blend Researchers at Schools (RAS) activities with European Researchers’ Nights (ERN) public events over the next two years.

What do the terms incidence and prevalence stand for? What do they measure? What are they used for?

Incidence and prevalence are two statistical measures of disease frequency that apply to any and every disease, although here we’ll just be concerned with cancer.

A portion of human gut – just removed from the abdomen of a colon cancer patient and opened in half so as to give access to its inner mucosa, – sits on the countertop. A technician starts to scan it with the tip of an optical fibre, hovering over the surface of the sample without touching it. On the scanned zones, streaks of various colours, as if the tissue is being “painted” by the laser beam coming out of the fibre optic.