18 August 2022
24 August 2022
Scientists from the Champalimaud Foundation discover how multiple myeloma cells disrupt immunity
One of the hallmarks of multiple myeloma (MM), a cancer of the bone marrow and one of the most frequent haematological cancers worldwide, is the disruption of the patients’ immune system, which allows the cancer to progress. Now, a study performed by Cristina João, who leads the Myeloma and Lymphoma Research Group at the Champalimaud Centre for the Unknown, and her colleagues, shows how so-called extracellular vesicles (EV’s) released by multiple myeloma cells can drive the disruption of the immune system.
28 July 2022
Science Snapshot: How Neuro-Immune Interactions Burn Deep Fat
06 July 2022
An Appetite Map in the Brain: How pregnancy and the lack of nutrients alter brain function to shape cravings
Let's face it. As enticing as the idea of starting lunch with a chocolate cake might be, few would actually make that choice when it comes down to it. And yet, at the end of the meal, many would reach for that same cake without hesitation.
The cause behind this phenomenon is the body's ever-changing internal states: by lunchtime, the body often needs protein, so the brain promotes that particular food choice. However, after the protein was ingested, carbs might be a nice extra for padding the body’s fat stores.
06 July 2022
Scientists discover how the brain keeps the urge to act in check
A study published today (July 6th) in the journal Nature, uncovers how the brain stops us from jumping the gun. "We discovered a brain area responsible for driving action and another for suppressing that drive. We could also trigger impulsive behaviour by manipulating neurons in these areas", said the study's senior author, Joe Paton, Director of the Champalimaud Neuroscience Programme in Portugal.
