Targeting TCR and Co-Receptor Signalling in T Cells Using Engineered Ligands

Host

Inês Ramos, PhD, Tissue Immunity


Venue

Seminar room

Multidisciplinary Recommendations on the Clinical Use of Psychedelic Substances

On the upcoming May 12th at 5:30 PM, the Auditorium of the Champalimaud Foundation will host a landmark event: the public presentation of the Multidisciplinary Recommendations on the Clinical Use of Psychedelic Substances.

29 April 2025

Champalimaud Foundation’s Henrique Veiga-Fernandes named Portugal’s sole ERC Ambassador

Chosen from over 200 applicants across Europe and associated countries, Veiga-Fernandes was one of just 32 scientists ultimately appointed as ERC Ambassadors. The final selection aimed to balance gender, seniority, and the representation of both current ERC grant holders and different countries. The 32 ambassadors represent 21 EU Member States and four Associated Countries – Israel, Norway, Turkey, and the United Kingdom – plus Switzerland.

16 April 2025

Research at Champalimaud Foundation Awarded 'Excellent' Rating in FCT's R&D Units Evaluation

This recognition affirms the dedication and collaborative effort of countless individuals over the years in building the diverse and sophisticated infrastructure necessary to support a world-class, cutting-edge biomedical research centre.

25 March 2025

In bowel cancer, enlarged lymph nodes can be a good prognostic feature

At the Champalimaud Colorectal Cancer Conference, last February, Gina Brown, from the Imperial College London, questioned the validity of the current staging strategy for colon cancer. Indeed, research shows that lymph nodes are not the main culprit in colon cancer spread, and can actually be a sign that the patient’s immune system is fighting back. 

19 March 2025

Can the microbiome provide information about the risk of developing colorectal cancer and its progression?

Coordinated by Professor Ana Santos Almeida, principal investigator of a translational laboratory at the GIMM Foundation - Gulbenkian Institute for Molecular Medicine (GIMM-CARE), this study will take place at the Champalimaud Foundation, in collaboration with Dr. José Azevedo, surgeon of the Colorectal Cancer Group of the Digestive Unit of the Champalimaud Clinical Center, and at the Hospital de Santa Maria, with the participation of oncologists Professor Luís Costa and Dr. André Mansinho.

Therapeutic Perspectives of Non-invasive Brain Stimulation: the Example of Chronic Pain Management

Host

Albino Oliveira-Maia, MD, PhD, Neuropsychiatry Unit


Venue

Seminar room

Home Sweet Home: Structure and Function of the Neurogenic Niche in Health and Disease

Host

Margarida Caio, Stem Cells and Regeneration Lab


Venue

Seminar room

12 March 2025

The secret DNA circles fueling Pancreatic Cancer’s aggression

A New Player in Pancreatic Cancer

The team found that some pancreatic cancer cells gain a major survival edge by carrying copies of critical cancer genes—such as MYC—on circular pieces of DNA that exist outside chromosomes, the structures that house most of our genetic material. Known as ecDNA, these genetic rings float freely in the cell nucleus, enabling tumour cells to swiftly ramp up gene expression, change their shape, and survive in otherwise hostile environments.

Under Pressure: How Mechanical Forces Influence Structural Plasticity

Host

Rita Cardoso-Figueiredo, Behavior and Metabolism Lab


Venue

Seminar room

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