Rita Fior

Group Leader
rita.fior@neuro.fchampalimaud.org
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Fior

Publications

Tavares Barroso, M.; Costa, B.; Rebelo de Almeida, C.; Castillo Martin, M.; Couto, N.; Carvalho, T.; Fior, R*. (2021)
Establishment of Pancreatobiliary Cancer Zebrafish Avatars for Chemotherapy Screening.
Cells (doi:https://doi.org/10.3390/cells10082077)
Póvoa, V, Rebelo de Almeida, C, Maia-Gil, M, Domingues, M, Martinez-Lopez, M, Almeida Fuzeta, M, Silva, C, and Fior, R*. (2021)
Innate immune evasion revealed in a colorectal zebrafish xenograft model
Nat Commun (doi:https://doi.org/10.1038/s41467-021-21421-y)
Martinez-Lopez, M, Póvoa, V and Fior,R*. (2021)
Generation of Zebrafish Larval Xenografts and Tumor Behavior Analysis.
JoVE
Poté N., Cros J., Laouirem S., Raffenne J., Negrao M., Albuquerque M., Bedossa P., Godinho Ferreira M., AIT-SI-ALI S., Fior R., and Paradis, V. (2020)
The histone acetyltransferase hMOF promotes vascular invasion in hepatocellular carcinoma.
Liver International.
Bruno L. Oliveira* Benjamin J. Stenton, Unnikrishnan V. B.,Cátia Rebelo Almeida, João Conde, Magda Negrão, Miguel Godinho Ferreira, Giovanni F. Caramori, Josiel B Domingos, Rita Fior* and Gonçalo J. L. Bernardes1,2*. (2020)
Platinum-triggered Bond-cleavage of Pentynoyl amide and N-propargyl handles for Drug-Activation
JACS (doi:DOI: 10.1021/jacs.0c01622)
Costa B, Estrada, M, Mendes RV and Fior R* (2020)
Zebrafish Avatars towards personalized medicine-a comparative review between Avatar models
Cells
Basti, A.; Fior, R.; Yalҫin, M.; Póvoa, V.; Astaburuaga, R.; Li, Y.; Naderi, J.; Godinho Ferreira, M.; Relógio, A. (2020)
The Core-Clock Gene NR1D1 Impacts Cell Motility In Vitro and Invasiveness in a Zebrafish Xenograft Colon Cancer Model
Cancers
Rebelo de Almeida; C, Mendes,R; Pezzarossa, A; Gago, J; Carvalho, C; Alves, A; Nunes, V; Brito, MJ; Cardoso, MJ; Ribeiro, J; Cardoso, F; Ferreira MG* and Fior, R*. (2020)
Zebrafish xenografts as a fast screening platform for bevacizumab cancer therapy.
Commun. Biol. (doi:https://doi.org/10.1038/s42003-020-1015-0)
Costa B, Ferreira S, Póvoa V, Cardoso MJ, Vieira S, Stroom J, Fidalgo P, Rio-Tinto R, Figueiredo N, Parés O, Greco C, Ferreira MG and Fior R. (2020)
Developments in zebrafish avatars as radiotherapy sensitivity reporters - towards personalized medicine.
EBIOMEDICINE
Varanda, A.B.; Martins-Logrado, A.; Godinho Ferreira, M.; Fior, R*. Cancers, (2020)
Zebrafish Xenografts Unveil Sensitivity to Olaparib beyond BRCA Status.
Cancers (doi:https://doi.org/10.3390/cancers12071769)
Povoa V, Fior R (2019)
Cancer Immunoediting and Hijacking of the Immune System
Springer
R Fior, R Zilhão (2019)
Molecular and Cell Biology of Cancer: When Cells Break the Rules and Hijack Their Own Planet.
Springer
Fernandes S.F., Fior R., Pinto F., Gama-Carvalho M. and Saúde L. (2018)
Fine-tuning of fgf8a expression through alternative polyadenylation has a selective impact on Fgf-associated developmental processes.
BBA Gene Regulatory Mechanisms. (doi: doi: 10.1016/j.bbagrm.2018.07.012. )
Fior R* and Ferreira MG* (2018)
Reply to Katsu and Baker: Using zebrafish PDX to screen drug sensitivity of endocrine-dependent cancers.
Proc Natl Acad Sci U S A (doi:doi:10.1073/pnas.1802639115)
Fior R, Póvoa V, Mendes RV, Carvalho T, Gomes A, Figueiredo N, Ferreira MG. (2017)
Single-cell functional and chemosensitive profiling of combinatorial colorectal therapy in zebrafish xenografts
Proc Natl Acad Sci U S A PNAS 2017 September, 114 (39), E8234-E8243 (doi: doi:10.1073/pnas.1618389114)
Fior R, Póvoa V, Mendes RV, Carvalho T, Gomes A, Figueiredo N, Ferreira MG. (2017)
Single-cell functional and chemosensitive profiling of combinatorial colorectal therapy in zebrafish xenografts
Proc Natl Acad Sci U S A PNAS 2017 September, 114 (39), E8234-E8243 (doi: doi:10.1073/pnas.1618389114)
Lopes SS, Distel M, Linker C, Fior R, Monteiro R, Bianco IH, Portugues R, Strähle U, Saúde L. (2016)
Report of the 4th European Zebrafish Principal Investigator Meeting.
Zebrafish 2016 Dec;13 (6), 590-595 (doi:10.1089/zeb.2016.1364)
Fior R, Maxwell AA, Ma TP, Vezzaro A, Moens CB, Amacher SL, Lewis J, Saúde L. (2012)
The differentiation and movement of presomitic mesoderm progenitor cells are controlled by Mesogenin 1
Development Dec;139(24): (139(24)), 4656-65 (doi:10.1242/dev.078923)
Cutty SJ, Fior R, Henriques PM, Saúde L, Wardle FC. (2012)
Identification and expression analysis of two novel members of the Mesp family in zebrafish
Int. J. Dev. Biol. 2012;56(4):285-94 (2012;56(4)), 285-94 (doi:10.1387/ijdb.113447sc.)
Fior R, Vilas-Boas F, Swedlow JR, Storey KG, Henrique D. (2011)
A novel reporter of notch signalling indicates regulated and random Notch activation during vertebrate neurogenesis
BMC Biol. Aug 31;9:58 (Aug 31;9:58), 9:58 (doi:10.1186/1741-7007-9-58)
Fior R, Henrique D. (2009)
"Notch-Off": a perspective on the termination of Notch signalling.
Int. J. Dev. Biol. 2009;53(8-10): (1379-84), 1379-84 (doi:10.1387/ijdb.072309rf)
Fior, R and Henrique D (2009)
NOTCH-MATHICS
American Mathematical Society & Real Sociedad Matemática Española
Fior R, Henrique D. (2005)
A novel hes5/hes6 circuitry of negative regulation controls Notch activity during neurogenesis.
Dev. Biol. 2005 May 15;281(2):318-33. (281(2):318-33.), 318-33. (doi:10.1016/j.ydbio.2005.03.017)
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