Marta Barbosa

Teresa Sotto Mayor

04 October 2023

Esketamine Nasal Spray: An Option for Patients with Treatment-Resistant Depression

Understanding Treatment-Resistant Depression

Treatment-resistant depression (TRD) is a particularly challenging form of major depressive disorder. As Albino Oliveira-Maia, head of the Champalimaud Foundation’s Neuropsychiatry Unit and the study’s national coordinator for Portugal, explains, “TRD is defined as the persistence of depressive symptoms despite adequate courses of at least two different antidepressant medications”. Despite repeated therapeutic attempts, these patients’ depressive symptoms remain.

Nuno Loução

Rita Cavaglià

Mariana Monteiro

Pedro Cruz

Joan Gort

08 September 2023

Ballet of the Brain: Unlocking the Choreography of Movement

Why we have a brain

“The brain’s primary function is movement”, explains Claudia Feierstein, lead author of the study published today in Current Biology. “Plants don’t need a brain because they don’t move. Yet, even for something as seemingly simple as eye movements, the brain’s role remains largely enigmatic. Our goal is to illuminate this ‘black box’ of motion and to decode how neural activity controls eye and body movements, using zebrafish as our model organism”.

Nico Espinoza

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