12 March 2025

The secret DNA circles fueling Pancreatic Cancer’s aggression

A New Player in Pancreatic Cancer

The team found that some pancreatic cancer cells gain a major survival edge by carrying copies of critical cancer genes—such as MYC—on circular pieces of DNA that exist outside chromosomes, the structures that house most of our genetic material. Known as ecDNA, these genetic rings float freely in the cell nucleus, enabling tumour cells to swiftly ramp up gene expression, change their shape, and survive in otherwise hostile environments.

Under Pressure: How Mechanical Forces Influence Structural Plasticity

Host

Rita Cardoso-Figueiredo, Behavior and Metabolism Lab


Venue

Seminar room

Spatial Omics and AI: Bridging Discovery and Translational Medicine

The "Spatial Omics and AI: Bridging Discovery and Translational Medicine" symposium, is a free event which will explore the impact of Spatial Proteomics and AI in Translational Research and Life Sciences.

Keynote speakers include: 

- Prof. Emma Lundberg (Stanford University)
- Dr. Andrea J. Radtke (Leica Microsystems)
- Dr. Thierry Nordmann (Max Planck Institute)
- Dr. Giuseppe Diaferia (Champalimaud Foundation)

05 March 2025

FUTURE-AI: The roadmap to reliable clinical AI

Developed by an international consortium of 117 experts in legal, ethical, clinical, and AI domains—and featuring Champalimaud Foundation (CF) Principal Investigator Nikolas Papanikolaou—the framework provides a detailed roadmap for creating trustworthy medical AI, from the earliest design stages all the way through clinical deployment and monitoring.

Diana Cadete

António Beltran

Margarida Fevereiro

Ana S. Santos

Niche Remodeling and Iron Metabolism in Acute Myeloid Leukemia

Host

Cristina João, PhD, Myeloma Lymphoma Research Group


Venue

Seminar room

21 Feb. 2025

Post-Doctoral Fellow in Pancreatic Cancer Research – Cancer Genome and Evolution Laboratory

Research
Application Starts: 21 Feb. 2025

We are seeking a highly motivated and skilled Post-Doctoral Fellow to join our dynamic research team at the Botton-Champalimaud Pancreatic Cancer Centre.

This prestigious center is dedicated to advancing pancreatic cancer research and treatment through innovative approaches and multidisciplinary collaboration. The successful candidate will contribute to cutting-edge research aimed at understanding the molecular mechanisms of pancreatic cancer progression and developing novel therapeutic strategies.

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