12 November 2020
04 November 2020
Predicting the outcomes of actions in order to make good decisions is a critical role of brain function. This process is thought to work through two fundamentally different mechanisms called “model-free” and “model-based” learning. Though fundamental for flexible and adaptive behaviour, the neurobiology of model-based learning remains poorly understood.
20 October 2020
Cannabinoids have a strong influence on how our brains work and how we behave. Many people are only aware of the recreational aspect of cannabinoids. But in fact these molecules naturally exist in our brains where they participate in various intrinsic processes.
Altered cannabinoid signalling, for instance due to chronic use of marijuana, results in a range of impairments. Similarly, mice lacking cannabinoid receptors exhibit reduced activity levels, as well as deficits in learning and memory.
01 October 2008
Seeking a place for Portugal among world’s scientific elite
October 5th 2008 marked an historic occasion not only for the nation of Portugal but also for the Champalimaud Foundation. As Portugal commemorated the anniversary of the creation of the Portuguese republic, work began on the Champalimaud Foundation’s new centre for cutting-edge translational research.